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broadinstitute
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adapt
A package for designing activity-informed nucleic acid diagnostics for viruses.
MIT License
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Implement objective function that maximizes expected activity
#23
haydenm
closed
4 years ago
0
Simplify making specific designs for a single taxon
#22
haydenm
closed
4 years ago
0
Accept serialized predictive models as input and use them
#21
haydenm
closed
4 years ago
0
Add executable to identify targets for testing
#20
haydenm
closed
4 years ago
0
Add trie sharding method to query the specificity of k-mers
#19
haydenm
closed
4 years ago
0
Add minor arguments useful in practice
#18
haydenm
closed
4 years ago
0
Change NCBI influenza database to fetch from
#17
haydenm
closed
4 years ago
0
Memoize specificity results for each guide
#16
haydenm
closed
4 years ago
0
Use predictive model of activity
#15
haydenm
closed
4 years ago
0
Rename project to 'adapt'
#14
haydenm
closed
4 years ago
0
Reduce required memory and runtime of guide memoization
#13
haydenm
closed
5 years ago
0
Add commands to design guides naively
#12
haydenm
closed
5 years ago
0
Add tool to analyze coverage of a design
#11
haydenm
closed
5 years ago
0
Automatically download and prepare input for design
#10
haydenm
closed
5 years ago
0
Add option to require flanking sequence (PFS) on guides
#9
haydenm
closed
5 years ago
0
Reduce runtime and memory usage on specificity queries
#8
haydenm
closed
5 years ago
0
Search simultaneously for primers and guides between those
#7
haydenm
closed
5 years ago
0
Tolerate G-U base pairing in guide-target binding
#6
haydenm
closed
5 years ago
0
Add options to require guides in the design and to blacklist from the design
#5
haydenm
closed
5 years ago
0
Consider multiple clusters when constructing guides
#4
haydenm
closed
5 years ago
0
Vary desired coverage of target sequences according to year
#3
haydenm
closed
6 years ago
0
Allow for differential identification, and other applications of locality-sensitive hashing
#2
haydenm
closed
6 years ago
0
Primer incorporation [Austin]
#1
austinreidmanny
closed
5 years ago
0
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