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I'd like to ask if it would be possible to support the alignment of DNA sequences using the C API? I would like to integrate `block-aligner` into an existing C/C++ tool but cannot use the exisiting C …
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Dotplot of two sequences from this alignment [ENSG00000006118.fa.zip](https://github.com/user-attachments/files/16790754/ENSG00000006118.fa.zip) is very odd.
```python
from cogent3 import load_ali…
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Hi! I'm writing with a question about input matrix size limits. I have a large alignment file-- 158 individuals, 49M sites, and I'm getting a segmentation fault error. Do you have any recommendations …
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Hi,
I wonder if anyone in this community can help me figure out the reason behind the discrepancy in counts. Please see below:
I am using HTSeq-count to generate counts from two different types …
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The gene alignment step can take a long time to complete. Is it possible to add functionality to output the unaligned gene sequences to later align batches of them across a computing cluster? The pira…
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**Lab Name**: Bioinformatics and Data Science in Biotechnology Lab
**Department**: Biotechnology and Biomedical Engineering
**List of Experiments and Repositories**:
1: Writing and…
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I have developed a bioinformatics pipeline that processes alignment results generated by minimap2, with an emphasis on minimizing the disk storage and maximizing analysis speed. To achieve this, I opt…
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### Operating System
Centos-7
### Other Linux
_No response_
### Workflow Version
v1.3.1
### Workflow Execution
CLI Cluster
### Other workflow execution
_No response_
###…
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Thank you for your excellent work! We know that the parameter 'blastx' can be used for DNA alignment. We have no idea if a DNA sequence can not be translated into protein sequence, can Diamond still …
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Hi,
I am interested in studying protein-nucleic acid couplings, like that of transcription factors and RNA binding proteins. I was looking at the plmc script and was wondering how I should go about…