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Hi Steven,
I have a WGS dataset with >100,000 samples. I used an initial set of 10,000 samples with an extracted VCF region for CYP2C9 to as a test run. Below is the command I used in PyPgx v0.19.0…
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Hello,
I am trying to run StellarPgx together with Docker (not Singularity) from within a Docker container. The whole "Docker in Docker" situation is still a bit confusing to me. However, what I ha…
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Hello,
I am trying to run Aldy to call CYP2D6 on a set of samples that were genotyped using PacBio long-read whole genome sequencing using 8x coverage. The current profiles available for Aldy use tar…
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Hello, I am fairly new to coding and I need some help implementing Cyrius in my project. I am currently trying to implement Cyrius in the All of Us cloud-based platform, but I am having trouble. All o…
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I first want to thank you for a great job with building and documenting the pypgx software. Really amazing and appreciated!!
I write because I get an error when running the ngs pipeline:
#######…
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Hello David! First of all thank you for sharing your scripts, I am currently interested in CYP2D6 genotyping and your resource has been really helpful.
Currently, I am running into a problem with A…
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### Model Name
Development of Robust Quantitative Structure-Activity Relationship Models for CYP2D6 Catalysis and Inhibition
### Model Description
Analysis of metabolic stability, determining the i…
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I have a set of 4 exomes and running aldy 4.4 on them as so:
aldy genotype -g cyp2e1 -p wxs ${bam_location}/*/${sample_name}.bam -o ${output}/${sample_name}.cyp2d6.aldy -l ${output}/${sample_name}…
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Hello, I've observed that I receive multiple recommendations for the same medication, especially for medications that involve more than one gene. For instance, when I run the code for amitriptyline an…
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* **Do you want to request a *feature* or report a *bug*?**
*bug*
* **What is the current behavior?**
* I am trying to use the latest version pharmcat-2.7.1-all.jar to generate a report. Wh…