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My protein sequence is from a mutant library, is it possible to speed up my protein structure prediction by changing the dataset? For example, without using the BFD dataset, if it is possible, how sho…
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This may be OK, but I think if this is a design choice it should be explicitly discussed as some global epistasis models (eg, Otwinoski et al) ensure that wildtype has a value of zero on both the late…
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Thanks for your great work!
I have set the Filtering Commands:
-b 500
-m median
--normal-cov 5
--normal-vaf 0.03
--tdna-cov 10
--tdna-vaf 0.05
but, the below result was in .all_epitopes.t…
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### Is there an existing issue for this?
- [X] I have searched the existing issues and checked the recent builds/commits
### What happened?
I go to generate art them get ValueError: not enough valu…
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Hello, I have recently read your latest paper "Accurate Mutation Effect Prediction using RoseTTAFold", a great work, and I want to try it, but I do not know how to mask out the amino acid in that muta…
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Hi!
I noticed that there is a discrepancy between the spearman correlations on the indel datasets for ProGen2 recorded in this repo and in the ProGen2 paper https://arxiv.org/pdf/2206.13517.pdf (Ta…
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Meta just released there LLaMA model family
https://github.com/facebookresearch/llama
Can we got support for that?
They calim that the 13B model is better than GPT 3 175B model
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**User Story**
Hi VariantValidator team, we got into some problems this morning using your tool and are trying to understand what is going wrong. We wanted to look at the consequence of deleting a wh…
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### Model Title
Ames Mutagenicity
### Publication
Hello @RoseZhen2022!
As part of your Outreachy contribution, we have assigned you the dataset "Ames Mutagenicity" from the Therapeutics Data Com…
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Hello ESM team,
I really appreciate your line of great works on protein language modeling.
I am wondering is it possible that you can share the raw prediction scores of each mutation for these 4…