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Hello
I was wondering if Clair would be a good tool to study locations of Cas9 mediated insertions? The insertions are ~2kbp long
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- different Cas enzymes
- different scores --> test how prediction changes
- include warnings for scores that are appropriate for certain applications or not (e.g. Cas9 derived scores vs Cas12 enzym…
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https://mp.weixin.qq.com/s/JB_CAwCl8nPmECuh0S5GaQ
ixxmu updated
2 months ago
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Hi,
I was trying to get set up on warpstr and use it to analyze some loci that we do have. Having installed it and updated the config file as asked in the README, I ran into some errors while runn…
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Hi,
Since I have updated from minimap2(v.2.17) to minimap2(v.2.24) supplementary alignments are now
specified as secondary alignments.
We perform CRISPR/Cas9 targeted nanopore sequencing to i…
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Hello,
I'm having issues while running CRISPRessoBatch for prime editing experiments. I've double checked my pegRNA spacer, pegRNA extension and the reference sequence, all are in the correct orien…
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# 生信爱好者周刊（第 102 期）：
这里记录每周值得分享的生信相关内容，周日发布。
本杂志开源（GitHub: [openbiox/weekly](https://github.com/openbiox/weekly)），欢迎提交 issue，投稿或推荐生信相关内容。
[「生信周刊讨论区」](https://github.com/openbiox/weekly/discuss…
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https://mp.weixin.qq.com/s/ENiwEEJOR4TZfIv1Majr6A
ixxmu updated
9 months ago
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Hi Matteo,
I've noticed a discrepancy between the information content matrix and flanking sequences in certain cases. I've attached one such example.
Here's the information content from downstre…
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https://mp.weixin.qq.com/s/FlO4fN5AlcyZ81llzHE5Ag
ixxmu updated
5 months ago