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There's a severe true path violation involving the component term 'immunoglobulin' (GO:0019814). It is listed as part of B-cell receptor complex, which in turn is part of apicolateral plasma membrane,…
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1. Host cell nuclear envelope
As a child of GO:0042025 host cell nucleus and GO:0033645 host cell endomembrane system
Def: The double lipid bilayer enclosing the host nucleus and separating its conten…
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I would like a few terms added, including regulation terms, covering processes of lymphocyte apoptosis.
The new term tree is as follows, and the explanations and term definitions follow.
apoptosis ;…
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Whilst requesting
https://sourceforge.net/p/geneontology/ontology-requests/10322/
I noticed that there are 2 branches leading to sets of which appear to mean the same thing but are not linked.
So,
F…
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Hi
please could the following term be created:
GO:0019221 cytokine and chemokine mediated signaling pathway
NTR: is_a interleukin-27-mediated signaling pathway
For use with gp130/IL6ST PMID:14764690…
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Pharmacological studies indicate that ryanodine receptors are the intracellular Ca2+ channels involved in cADPR induced Ca2+ release. see PubMed 11752598. maybe consider this paragraph in PubMed:10759…
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I found 'histamine secretion' and 'histamine secretion involved in inflammatory response' in GO, but no histamine secretion that is mediated by immunoglobulins. Is this a term that is within your scop…
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Hi (Paola?),
sorry, this is am long one!
I’ve been making several new GPCR related complexes and noticed some holes and inconsistencies in the GO. The main problem lies in the CC branch but I will n…
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Hi
I think I may have raised this issue before, but can't remember what I listed this under.
Basically gp130 is a subunit of several IL receptors, eg IL6, IL27 as well as non interleukin receptors s…
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is_a GO:0033212 ! iron assimilation ***
is_a GO:0033213 ! iron assimilation by capture and transport [has_part: "iron ion transmembrane transport"]
is_a GO:0033214 ! …