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Update the following URL to point to the GitHub repository of
the package you wish to submit to _Bioconductor_
- Repository: https://github.com/ErasmusMC-CCBC/katdetectr
Confirm the following b…
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Hi,
Running function combineBCR() is very slow for me, comparing to relatively faster computation for combineTCR(), using the same number of samples and similar data size. I wonder what could be th…
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There are a few reasons this may be a bad approximation:
* the outcome variable is the expected number of substitutions per site (ESS), which is like a transformation of the count outcome (number of …
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# BCR support meta issue.
## Initial PR #183 addresses:
- [x] change datastructure
* Instead of `TRA_1`, `TRA_2`, `TRB_1` and `TRB_2` have `arm1_primary`, `arm1_secondary`, `arm2_primary` an…
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Hello,
Thanks for the great software. I have a question regarding the report in tsv format.
Seems the values in column "frequency" sum up to 2, not 1. Could I understand why? Below is an example…
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Hello,
I've downloaded latest version v1.0.2 and tested it with dataset I processed via an earlier version downloaded in July, 2020. I found that in the tsv file, there are two additional columns '…
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Hi, Sigven, PCGR can analysis MSI and mutational signatures. Would you like to add Kataegis in the future?
You can see the Kataegis from mutalisk (http://mutalisk.org).
thanks!
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Thank you for developing this useful tool. I am planning to get TCRs and BCRs from RNA-seq data with MiXCR. BCR has somatic hypermutations, so it should be more difficult to get. Can I ask for the bes…
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https://shixiangwang.github.io/sigminer/reference/handle_hyper_mutation.html