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Hello,
I was comparing the outputs from MiXCR and Cellranger and I noticed that there are some differences between number of cell barcodes identified and the chains it gets assigned with. I was fi…
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## 🐛 Bug
repLoad fails to load data
## To Reproduce
Steps to reproduce the behavior:
1. run repLoad with path to csv files
TRB
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Hello, when looking at the mixcr report, I find two TCR repertoires with exactly identical CDR3 amino acid sequences and 1 mismatch in CDR3 nt sequences. These two occurrences have equal V and J segme…
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Hi,
I'd like to measure the AA distance between all pairs of TCRs based on their alpha and beta CDR3 AA sequences, per each pair of TCRs with the same V(D)J sequence IDs (and I'd also like to do th…
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Good morning,
Would you please provide some details about how two functions "clonalHomeostasis" and "clonalProportion" per sample and per seurat clusters, are working?
Thanks!
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Hi I'm new to T cell receptors and [Adaptive Immune Receptor Repertoire](https://www.antibodysociety.org/the-airr-community/) and I have some question (I'm not sure if they would be better in slack or…
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Based on the guide of generic-amplicon preset, the reads are constructed as follows.
The read outputs that I am trying to process through MiXCR, however, looks like this. R2 has the UMI sequence…
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Hello,
IS combineTRUST4 works in new version of scRepertoire?
It is giving me error:
could not find function "combineTRUST4"
Thanks for your help!
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Hello,
TCRdist is a great package. I appreciate its development!
I am attempting to perform an analysis on my dataset; however, I am not sure how to best achieve it.
I currently have two cond…
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Hello,
I am trying to decide on whether the new version of MIXCR is compatible for our TCR seq pipeline.
Our TCR Seq pipeline is based on the paper "RNase H-dependent PCR-enabled T Cell Receptor…