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# Issue Report
## Please describe the issue:
I have fast5-files and wanted to basecalling with Dorado. These files had previously been analyzed, I thing with Guppy and we wanted to reproduce the r…
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Dear authors,
I have a question regarding the detection of methylations. I am not quite sure how it detects gold methylations, i.e. is it based on already existing methylation patterns (motifs) an…
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Hello,
I'm using racon to polish a close-to-complete genome assembly where most contigs have telomeres on the end. Racon is removing many of these telomeres. Is there any way I can avoid racon remo…
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[ReferenceDatabase_text.txt](https://github.com/polio-nanopore/piranha/files/14496836/ReferenceDatabase_text.txt)
Hi, I'm struggling to get the phylo module to add the supplementary-datadir to the …
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Just wanted to ask if there are any plans on releasing a `guppy >= v6` base calling of the reads?
Thanks.
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Thank you for your great contribution, but we still meet some difficulties using this soft.
1. running Assemblymapper, error information is "FileNotFoundError: [Errno 2] No such file or directory: '…
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Is there a set of documentation for Remora to get us started? We have a set of data ready but are having trouble getting started. We are interested in damaged base sequencing. Also, are the oligo sequ…
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Hi everyone,
First of all, thanks for the nice program, I'm excited to have it aaalmost working... After few days handling all the problems with the permissions, I'm trying to run the tutorial exper…
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Hi all. I'm trying to polish an assembly from Flye for nanopore reads. However, I cannot make the command work as I receive errors that I cannot determine the source, or how to proceed. These errors a…
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I am trying to use this to assembly the nanopore reads, but when I run the hinge clip step, I got this error message.
"'
raymond:$hinge clip-nanopore ecoli.edges.hinges ecoli.hinge.list t1
/opt…