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cc @ValWood and @kimrutherford
Today I was curating a paper in which they show that:
* deletion of gene X causes an increase in protein A levels
* deletion of gene Y causes an equal / very simila…
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Background:
Q from JAcky:
Are all genetic interactions between 2 genes in the Genetic Interaction section of a gene page or just high through put data. Tiffany asked me if she could find out if a …
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We can probably make some conversions for the interaction types.
1. For any legacy GI "synthetic lethal", convert to new style, as long as there are phenotypes for
term FYPO:0002061 inviable v…
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Sessions with both style:
from https://github.com/pombase/website/issues/1348
current list here:
https://github.com/pombase/curation/issues/3365#issuecomment-1302162427
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add the protein interaction data from wormbase.
note that these encompass genetic and physical interactions, as well as group-wise interactions in complexes, which requires a bit of modeling.
the …
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Term 219 is showing multiple interactions of the same type between Atg8 and Snx4 in the interaction table for co-expression and conditional genetic interactions. Just checked the version of the table…
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**Authors:** Benjamin C. Haller, Philipp W. Messer
**Abstract:** Individual-based, genetically-explicit modeling is an essential tool for connecting empirical population genetic patterns to hypothe…
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This should be automated somehow. All new interaction annotations will come from Canto. That may help as those annotations always have dates attached.
Original comment by: kimrutherford
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A good question from @kyook (see the slides in Dropbox for background)
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I don’t understand where gene interactions are accounted for. We separate genetic background - like in your example of the …
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Some terms in this ontology are marked as obsolete, but not alternatives are given. For example, the majority of the interactions defined in BioGRID (https://thebiogrid.org/) are annotated the term MI…