bcgsc / mavis

Merging, Annotation, Validation, and Illustration of Structural variants
http://mavis.bcgsc.ca
GNU General Public License v3.0
72 stars 13 forks source link
bioinformatics genomics python structural-variation transcriptome visualization

![PyPi](https://img.shields.io/pypi/v/mavis.svg) ![build](https://github.com/bcgsc/mavis/workflows/build/badge.svg?branch=master) [![codecov](https://codecov.io/gh/bcgsc/mavis/branch/master/graph/badge.svg)](https://codecov.io/gh/bcgsc/mavis) ![ReadTheDocs](https://readthedocs.org/projects/pip/badge/) ## About [MAVIS](http://mavis.bcgsc.ca) is python command-line tool for the post-processing of structural variant calls. The general [MAVIS](http://mavis.bcgsc.ca) pipeline consists of six main stages - convert - [cluster](https://mavis.readthedocs.io/en/latest/package/mavis/cluster) - [validate](https://mavis.readthedocs.io/en/latest/package/mavis/validate) - [annotate](https://mavis.readthedocs.io/en/latest/package/mavis/annotate) - [pairing](https://mavis.readthedocs.io/en/latest/package/mavis/pairing) - [summary](https://mavis.readthedocs.io/en/latest/package/mavis/summary) ## Getting Help All steps in the MAVIS pipeline are called following the main mavis entry point. The usage menu can be viewed by running without any arguments, or by giving the -h/--help option ``` bash mavis -h ``` Help sub-menus can be found by giving the pipeline step followed by no arguments or the -h options ``` bash mavis cluster -h ``` Common problems and questions are addressed on the [wiki](https://github.com/bcgsc/mavis/wiki/Help-and-Frequently-Asked-Questions). If you have a question or issue that is not answered there (or already a github issue) please submit a github issue to our [github page](https://github.com/bcgsc/mavis/issues) or contact us by email at [mavis@bcgsc.ca](mailto:mavis@bcgsc.ca) ## Getting Started The simplest way to use MAVIS is via Singularity. The MAVIS docker container used by singularity will take care of installing the aligner as well. ```bash pip install -U setuptools pip wheel pip install mavis_config # also installs snakemake ``` Now you will run mavis via Snakemake as follows ```bash snakemake \ -j \ --configfile \ --use-singularity \ -s Snakefile ``` For other installation options which do not use docker/singularity see the comprehensive install instructions in the [user manual](https://mavis.readthedocs.io/en/latest/install) ## Citation If you use MAVIS as a part of your project please cite [Reisle,C. et al. (2018) MAVIS: Merging, Annotation, Validation, and Illustration of Structural variants. Bioinformatics.](https://doi.org/10.1093/bioinformatics/bty621)