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Good day,
I would like to perform Differential methylation scoring.
Is there a way to identify the number of hypo and/or hyper differentially methylated regions in introns, exons, promoters, TSS, 5′…
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Dear m6A developers.
I wonder if you can advise on the best statistics to perform a differential m6A abundance analysis between two sample groups.
I've already successfully run m6anet v2.1 on my O…
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I can't find the differential methylation analysis workflow
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Hello @alexg9010 . I do have an unbalanced number of replicates for my conditions. For example, one condition A has 5 replicates B - 3 and C - 4. Can methylKit handle these uneven numbers of replicat…
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Hi, thank you for creating and maintaining this excellent tool. I have encountered a few questions while using `modkit` for m6A detection.
1. **Extension of Regions with `modkit pileup` and `modkit…
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Hello MerenLab,
While at EBAME I was encouraged to open this discussion by @FlorianTrigodet and @ivagljiva, and bring it to @semiller10's attention.
DNA methylation is on the verge of constituti…
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'Warning: Error in combn: n < m' comes up no matter what parameters I select. How do I switch the n and m?
John
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Thank you for this wonderful package.
I was looking through the vignettes on differential methylation, and was wondering if for my dataset I have multiple samples from the same individuals from di…