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**Background**
In some cases there is no need to divide modified nucleotides to submonomers (sugar, base, phosphate). Such nucleotides should be supported as single monomers.
**Requirements**
1.…
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Hi
I have data from multiple Illumina MiSeq runs, that I want to analyze together. Some of the runs were sequenced with a v2 kit (2x250 cyc), some with a v3 kit (2x300 cyc). All of the runs cover t…
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Hi,
I tried using many names but could not figure out the issue. I thought I gave the wrong genome name.
Furthermore, I'd like to know what I should substitute for **genome**.
Python download_k…
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This PK: be8dbb09-25da-4592-b00c-289922a5bf2c
Shows some warnings for ARAGORN
https://arax.ncats.io/?r=d6a12851-c7da-443b-a333-15d816f3a8af
https://arax.ci.transltr.io/?r=be8dbb09-25da-4592-…
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**Describe the bug**
NM_020451.2:c.827_829dup > NP_065184.2:p.(Val275_Ala276=)
**Expected behavior**
To be confirmed
This is a weird one. Mutalyzer shows 2 alternate descriptions. I have added…
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Hello,
The oxDNA2_sequence_dependent_parameters.txt file provides modifiers for the stacking interaction between each pair of nucleotides. As I understand the notation, the parameter STCK_G_C modif…
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I am aligning a very simple example with exact match (see below). For some reason 2 nucleotides are separated from the rest and placed in the very end. Input and output attached.
![image](https://git…
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#### Current behavior:
44 genes are discovered to be uncorrelated with their corresponding reactions in Transport reactions.
| Gene| UniProtID| Reaction| GPR| Correlation| Manually check|
|…
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# Issue Report
I am running dorado demultiplexing using custom barcodes, and the majority of my reads end up unclassified.
My custom TOML file includes the following trailing flank:
mask1_re…
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The HGVSp field is empty for variants in the intron or in the UTR. The correct HGVS description for not expecting a change on protein level would actually be `p.(=)`. In case the variant is inside a s…