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It seems like karyoploteR is computing coverage in a different way than IGV.
I think that IGV is ignoring the reads that have pairs mapping outside the viewing region. In contrast, karyoploteR is i…
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**Date**: May 14th 2024
**Time**: 2pm UK time [other timezones](https://www.timeanddate.com/worldclock/meetingdetails.html?year=2024&month=5&day=14&hour=13&min=0&sec=0&p1=43&p2=136&p3=37&p4=771&p5=23…
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I recently mapped a number of M.tuberculosis RNAseq samples against an M.tuberculosis reference, and I noticed that STAR (v2.7.5b) is reporting a small, but non-zero number of fragments spanning splic…
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Hi there,
I am trying to diffuse a binder of length 20 to the X chain of the protein "2O26."
But I can't seem to get around this error. If this is an issue within the PDB file, I would appr…
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Hi @diogomart,
I'm trying to optimize Vina parameters to get better agreement with experiment for docked binding energies of small molecules to cyclodextrins. To do this, I'd like to be able to tak…
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**What is your question?**
I got a "Not enough GPU memory error" when using a 3440 a.a. sequence as input.
"2023-03-20 17:54:52,116 Could not predict N_Repeat_C. Not Enough GPU memory? RESOURCE_EX…
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Last year at BioITWorld I chatted to sofware vendors who had various snazzy 3D features with a view to them searching some OSM frontrunners. I have to say, beyond polite interest, traction was mor…
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Hi Brady,
I have a local PDB file, attached as [CTD.zip](https://github.com/BradyAJohnston/MolecularNodes/files/8644818/CTD.zip). It is self-generated so that it has nothing else but only the atom…
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[Rosetta](https://www.rosettacommons.org/software) is a unique and powerful piece of software, but it appears like there isn't a current open source equivalent ([discussion](https://twitter.com/rbhar9…
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When testing the new protein chain grounding feature, I found something odd, namely, several synonyms that I confirmed to be listed in `uniprot-proteins.tsv.gz`, e.g., `Spike glycoprotein` were not re…