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PMID: 30874562 A phosphorylated transcription factor regulates sterol biosynthesis in Fusarium graminearum
#163
MPiovesana
closed
4 months ago
23
PMID: 24903410 Protein kinase FgSch9 serves as a mediator of the target of rapamycin and high osmolarity glycerol pathways and regulates multiple stress responses and secondary metabolism in Fusarium graminearum.
#162
MPiovesana
closed
4 months ago
13
PMID: 23629718 Molecular mechanisms of drug resistance in clinical Candida species isolated from Tunisian hospitals
#161
MPiovesana
closed
3 months ago
12
PMID: 9758830 A novel ATP-binding cassette transporter involved in multidrug resistance in the phytopathogenic fungus Penicillium digitatum
#160
MPiovesana
closed
5 months ago
10
PMID: 12019099 An Enterococcus faecalis ABC homologue (Lsa) is required for the resistance of this species to clindamycin and quinupristin-dalfopristin.
#159
MPiovesana
closed
4 months ago
11
PMID: 11600353 In vitro and in vivo effects of 14alpha-demethylase (ERG11) depletion in Candida glabrata.
#158
MPiovesana
closed
9 months ago
14
When to use transformant allele?
#157
MPiovesana
opened
1 year ago
51
PMID:28630186 Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis.
#156
MPiovesana
closed
3 months ago
6
PMID:15917566 Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility.
#155
MPiovesana
closed
9 months ago
10
PMID:11418514 Resistance to itraconazole in Aspergillus nidulans and Aspergillus fumigatus is conferred by extra copies of the A. nidulans P-450 14alpha-demethylase gene, pdmA.
#154
MPiovesana
closed
3 months ago
9
PMID: 12612806 Characterization of spontaneous mutants of Magnaporthe grisea expressing stable resistance to the Qo-inhibiting fungicide azoxystrobin
#153
MPiovesana
opened
1 year ago
14
PMID: 10919801 Tandem Repeat of a Transcriptional Enhancer Upstream of the Sterol 14α-Demethylase Gene (CYP51) in Penicillium digitatum
#152
MPiovesana
closed
1 month ago
15
PMID: 2946938 Cloning and characterization of the gene for beta-tubulin from a benomyl-resistant mutant of Neurospora crassa and its use as a dominant selectable marker
#151
MPiovesana
closed
11 months ago
9
PMID: 20019793 Fungicide-driven evolution and molecular basis of multidrug resistance in field populations of the grey mould fungus Botrytis cinerea
#150
MPiovesana
closed
3 months ago
10
PMID24119086: Site-directed mutagenesis of the P225, N230 and H272 residues of succinate dehydrogenase subunit B from Botrytis cinerea highlights different roles in enzyme activity and inhibitor binding
#149
jingluodatacurator
opened
1 year ago
11
PMID: 28456312 Characterization of boscalid-resistance conferring mutations in the SdhB subunit of respiratory complex II and impact on fitness and mycotoxin production in Penicillium expansum laboratory strains
#148
MPiovesana
closed
11 months ago
4
PMID: 26220356 Mutation of G234 amino acid residue in candida albicans drug-resistance-related protein Rta2p is associated with fluconazole resistance and dihydrosphingosine transport
#147
MPiovesana
closed
3 months ago
11
PMID: 25758923 Functional analysis of the Fusarium graminearum phosphatome
#146
MPiovesana
closed
8 months ago
14
PMID14693557 FKS1 Mutations Responsible for Selective Resistance of Saccharomyces cerevisiae to the Novel 1,3--Glucan Synthase Inhibitor Arborcandin C
#145
jingluodatacurator
closed
1 year ago
5
PMID: 22912706 Functional and structural comparison of pyrrolnitrin- and iprodione-induced modifications in the class III histidine-kinase Bos1 of Botrytis cinerea
#144
MPiovesana
closed
11 months ago
24
PMID: 27799210 Screening and Characterization of a Non-cyp51A Mutation in an Aspergillus fumigatus cox10 Strain Conferring Azole Resistance
#143
MPiovesana
opened
1 year ago
12
PMID: 32569396 Mutations at sterol 14α-demethylases (CYP51A&B) confer the DMI resistance in Colletotrichum gloeosporioides from grape.
#142
MPiovesana
closed
9 months ago
13
PMID:18443110 A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility.
#141
CuzickA
closed
1 year ago
10
PMID:15215142 Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs.
#140
CuzickA
opened
1 year ago
29
PMID: 9871122 A single amino-acid substitution in the iron-sulphur protein subunit of succinate dehydrogenase determines resistance to carboxin in Mycosphaerella graminicola
#139
MPiovesana
opened
1 year ago
7
PMID: 22536383 Mutagenesis and Functional Studies with Succinate Dehydrogenase Inhibitors in the Wheat Pathogen Mycosphaerella graminicola.
#138
MPiovesana
opened
1 year ago
14
PMID: 16801438 A Phe389Leu substitution in ergA confers terbinafine resistance in Aspergillus fumigatus
#137
MPiovesana
closed
9 months ago
9
PMID: 17371828 A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations
#136
MPiovesana
opened
1 year ago
18
PMID: 12543662 Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase
#135
MPiovesana
closed
9 months ago
12
Can we curate genetic crosses?
#134
MPiovesana
opened
1 year ago
2
PMID:15345450 Implications of amino acid substitutions in GyrA at position 83 in terms of oxolinic acid resistance in field isolates of Burkholderia glumae, a causal agent of bacterial seedling rot and grain rot of rice
#133
MPiovesana
closed
4 months ago
15
PMID: 15215099 Extra copies of the Aspergillus fumigatus squalene epoxidase gene confer resistance to terbinafine: genetic approach to studying gene dose-dependent resistance to antifungals in A. fumigatus
#132
MPiovesana
closed
9 months ago
10
PMID: 8641470 Site-directed mutagenesis of Saccharomyces cerevisiae beta-tubulin: Interaction between residue 167 and benzimidazole compounds.
#131
MPiovesana
closed
9 months ago
9
PMID: 12604551 A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus
#130
MPiovesana
closed
9 months ago
12
PMID: 12135574 An osmosensing histidine kinase mediates dicarboximide fungicide resistance in Botryotinia fuckeliana (Botrytis cinerea)
#129
MPiovesana
closed
2 months ago
6
PMID: 23226235 Discovery of a HapE mutation that causes azole resistance in Aspergillus fumigatus through whole genome sequencing and sexual crossing
#128
MPiovesana
closed
2 months ago
9
PMID: 16723566 Assessing resistance to the echinocandin antifungal drug caspofungin in Candida albicans by profiling mutations in FKS1
#127
MPiovesana
closed
12 months ago
26
PMID: 26092798 A gene locus for targeted ectopic gene integration in Zymoseptoria tritici
#126
MPiovesana
closed
11 months ago
25
Decide what do to when curators use different UniProt ids for the same gene in different publications
#125
CuzickA
opened
1 year ago
21
PMID: 31860693 A dispensable paralog of succinate dehydrogenase subunit C mediates standing resistance towards a subclass of SDHI fungicides in Zymoseptoria tritici
#124
CuzickA
opened
1 year ago
26
PMID: 25627815 Fungicide efflux and the MgMFS1 transporter contribute to the multidrug resistance phenotype in Zymoseptoria tritici field isolates
#123
CuzickA
closed
3 months ago
22
‘Suggest a new child term’ link is misleading in some cases
#122
CuzickA
closed
11 months ago
44
PMID:34490974 Directed evolution predicts cytochrome b G37V target site modification as probable adaptive mechanism towards the QiI fungicide fenpicoxamid in Zymoseptoria tritici.
#121
CuzickA
closed
1 year ago
34
PMID:22045588 Strong resistance to the fungicide fenhexamid entails a fitness cost in Botrytis cinerea, as shown by comparisons of isogenic strains.
#120
CuzickA
closed
8 months ago
28
PMID:30911085 Phenylpyrrole fungicides act on triosephosphate isomerase to induce methylglyoxal stress and alter hybrid histidine kinase activity.
#119
CuzickA
closed
1 year ago
0
PMID: 18779358 Genetic Analysis of Fenhexamid-Resistant Field Isolates of the Phytopathogenic Fungus Botrytis cinerea
#118
CuzickA
closed
11 months ago
12
PMID: 20305029 Heterologous Expression of Mutated Eburicol 14-Demethylase (CYP51) Proteins of Mycosphaerella graminicola To Assess Effects on Azole Fungicide Sensitivity and Intrinsic Protein Function
#117
CuzickA
closed
1 year ago
2
PMID:16048935 Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates.
#116
CuzickA
closed
9 months ago
33
Notes on curating Chemistry papers
#115
CuzickA
opened
1 year ago
6
Unused genes in curation sessions
#114
jseager7
opened
1 year ago
12
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