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Dear Dr. Sean,
I hope this message finds you well. I am writing to express my admiration for your recent publication in Current Biology titled "High viral abundance and low diversity are associated…
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Hi, all
I used this nice tool to identify CRISPR-Cas systems for my assembled MAGs. However, the result of the output file (CRISPR-Cas_summary.tsv) doesn't have Cas and Cas Types/Subtypes. Why? Whe…
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Hi,
Thank you for creating a great platform to examine the CRISPR-Cas transposon systems bioinformatically!
I was able to follow along the tutorial to find CRISPR and Cas proteins in the genome o…
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I was playing around with the `crispr` module and came across a weird error where the cut coordinates of a `cas9` object were way larger than the target sequence.
```
from pydna.dseqrecord import …
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CRISPR systems are classified into types based on which *cas* genes they have. The current [classification system](http://dx.doi.org/10.1038/nrmicro3569) (ping me for pdf) divides CRISPR systems into …
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Hello, it's very interesting to use the interaction features between molecules as encoding inputs for prediction models.
Can we use the features of the 256 simulated RNA-DNA hybrids that you menti…
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I'd like to be able to design CRISPR guide RNAs with Poly. Below is a draft spec for a new CRISPR package:
## Spec
Our guide RNA design package should be lightweight and easily extendable and at…
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Hi,
I'm trying to run the Singularity version of CRISPRCasFinder (version 4.2.20) with the -faa and -gff options (I generated my GFF file using the Dfast annotator, see below), but I'm getting the …
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[I advise holding off on this ticket for now but I need a place to make some initial notes. I will be editing this ticket as I go along]
I am with @dustine32 looking at integrating the TCs @thomasp…
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Artificial womb development brings new hope for some preemies:
https://www.fox16.com/donna-terrells-family-health/artificial-womb-development-brings-new-hope-for-some-preemies/